Preclinical Service Analytics

Analytical Services for Ames Test, Chromosomal Aberration, in vitro Dermal Permeation, Skin Irritation, Sensitization

Analytical Services for in vitro toxicology assessments

Ames Test : Bacterial Mutagenicity Assay in Agar Plate or Fluctuation Test, OECD 471
Ames Test : Treat & Wash Method for His-containing testcompounds (antibodies, proteins, etc), OECD 471
Ames Test: Genotoxic Impurities, Extractables, Leakables ICH M7

Chromosomal Aberration: Mammalian Chromosome Aberration Test (OECD473)
Chromosomal Aberration : Micronucleus (OECD 487)

Endocrine Disruptor Chemicals EDC: Testing for estrogen and/or endrogen receptor activity OECD 455

Dermal in vitro Permeation Testing IVPT: Skin Absorption, Skin Penetration Testing (OECD 428 and MDR EU Reg. 2017/745)
Skin Irritation OECD 439
Skin Sensitization (OECD TG 442D, DPRA)

Cytotoxicity for mammalian cells ISO10993-5

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Analytical Services for Environmental Samples: Yeast Estrogen & Androgen Screening for Endocrine Disruptive Chemicals EDC, Ames Test

- Screening Test for Endocrine Disruptor Chemicals : Yeast estrogen Screen YES and Yeast Androgen Screen YAS including antagonistic activity

- Mutagenicity/Genotoxicity for drinking, surface and waste water, soil, air : (Ames MPF 98/100 Aqua (ISO11350), Ames II, Ames Plate Incorporation Assay (OECD 471, ISO/FDIS 13820)

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